Best Flea and Tick Preventions for Dogs Updated July 2025

Join the millions that have trusted BuyersGuide.org to help them make smarter buying decisions. Let our independent expert reviews and data-driven shopping recommendations help you find the one that's right for you.

Best Flea and Tick Preventions for Dogs
2025 Buyer's GuideUpdated July 2025
Sort by:

10.0

1

10.0

Flea and Tick Prevention for Dogs Chewables - Made in USA - Natural Flea and Tick Chews Supplement - Oral Pills for Dogs - Pest...
Functionality
Flea prevention
Taste
Ease of giving
Natural ingredients
Side effects
Picked by 366 people this week!
Picked by 366 people this week!

10.0

1
Flea and Tick Prevention for Dogs Chewables - Made in USA - Natural Flea and Tick Chews Supplement - Oral Pills for Dogs - Pest...
Functionality
Flea prevention
Taste
Ease of giving
Natural ingredients
Side effects

9.9

2

9.9

Advecta Ultra Flea And Tick Prevention For Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - XL, Fast Acting Wa...
Value for money
Ease of application

9.9

2
Advecta Ultra Flea And Tick Prevention For Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - XL, Fast Acting Wa...
Value for money
Ease of application

9.5

3

9.5

Seresto Large Dog Vet-Recommended Flea & Tick Treatment & Prevention Collar for Dogs Over 18 lbs. | 8 Months Protection
Functionality
Flea control
Durability
Side effects

9.5

3
Seresto Large Dog Vet-Recommended Flea & Tick Treatment & Prevention Collar for Dogs Over 18 lbs. | 8 Months Protection
Functionality
Flea control
Durability
Side effects

9.4

4

9.4

Vet's Best Flea and Tick Home Spray – Plant-Based Flea and Tick Treatment for Dogs and Indoor Use – Natural Spray with Essentia...
Functionality
Safety for pets
Natural ingredients

9.4

4
Vet's Best Flea and Tick Home Spray – Plant-Based Flea and Tick Treatment for Dogs and Indoor Use – Natural Spray with Essentia...
Functionality
Safety for pets
Natural ingredients

9.2

5

9.2

K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 6-Mo Supply
Effectiveness
Repels flea and tick
Dog health
Ease of application

9.2

5
K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 6-Mo Supply
Effectiveness
Repels flea and tick
Dog health
Ease of application

9.0

6

9.0

FRONTLINE Plus for Dogs Flea and Tick Treatment (Large Dog, 45-88 lbs.) 3 Doses (Purple Box)
Ease of application
Dog health
Protection level

9.0

6
FRONTLINE Plus for Dogs Flea and Tick Treatment (Large Dog, 45-88 lbs.) 3 Doses (Purple Box)
Ease of application
Dog health
Protection level

8.8

7

8.8

Frontline Plus Flea and Tick Treatment for Medium Dogs Up to 23 to 44 lbs. 3 Treatments
Ease of application
Tick resistance
Durability

8.8

7
Frontline Plus Flea and Tick Treatment for Medium Dogs Up to 23 to 44 lbs. 3 Treatments
Ease of application
Tick resistance
Durability

8.7

8

8.7

PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting, Large D...
Quality
Ease of application

8.7

8
PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting, Large D...
Quality
Ease of application

8.5

9

8.5

Advecta Ultra Flea And Tick Prevention For Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - Large, Fast Acting...
Value for money
Ease of application

8.5

9
Advecta Ultra Flea And Tick Prevention For Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - Large, Fast Acting...
Value for money
Ease of application

8.3

10

8.3

Frontline Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments
Product quality
Dog health
Ease of application
Tick resistance

8.3

10
Frontline Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments
Product quality
Dog health
Ease of application
Tick resistance

Our Top Choice

10.0

1

10.0

Flea and Tick Prevention for Dogs Chewables - Made in USA - Natural Flea and Tick Chews Supplement - Oral Pills for Dogs - Pest...
Functionality
Flea prevention
Taste
Ease of giving
Natural ingredients
Side effects
Picked by 366 people this week!
Picked by 366 people this week!

10.0

1
Flea and Tick Prevention for Dogs Chewables - Made in USA - Natural Flea and Tick Chews Supplement - Oral Pills for Dogs - Pest...
Functionality
Flea prevention
Taste
Ease of giving
Natural ingredients
Side effects