Best Enzyme Drain Cleaners Updated May 2025
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Best Enzyme Drain Cleaners
2025 Buyer's GuideUpdated May 2025
Advertiser disclosure About our rankings
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Best Enzyme Drain Cleaner

10.0

1

10.0

Bioda Professional Strength Enzyme Drain Cleaner, Septic Safe Drain Odor Eliminator, Smell Eliminator
Functionality
Smell
Drain cleaning
Read Full Review
Picked by 354 people this week!
Picked by 354 people this week!
Picked by 354 people this week!
Best Enzyme Drain Cleaner

10.0

1
Bioda Professional Strength Enzyme Drain Cleaner, Septic Safe Drain Odor Eliminator, Smell Eliminator
Functionality
Smell
Drain cleaning
Picked by 354 people this week!
Read Full Review
Best Value

9.7

2

9.7

Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & ...
Ease of use
Safety
Taste
Save 13%
Save 13%
Best Value

9.7

2
Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & ...
Ease of use
Safety
Taste
Save 13%

9.4

3

9.4

Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Pet Stain and Odor Remover, Drain Cleaner - Powerful Cleaning & Odor E...
Scent
Works well
Cleaner effectiveness
Value for money
Enzyme effectiveness
Pet safety

9.4

3
Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Pet Stain and Odor Remover, Drain Cleaner - Powerful Cleaning & Odor E...
Scent
Works well
Cleaner effectiveness
Value for money
Enzyme effectiveness
Pet safety
Premium Pick

9.2

4

9.2

Drain Field Cleaner Tablets by Dr Pooper. Clears Septic Tanks and Drain Fields of Tough Clogs, Scum, Sludge AND Eliminates Odor...
Ease of use
Premium Pick

9.2

4
Drain Field Cleaner Tablets by Dr Pooper. Clears Septic Tanks and Drain Fields of Tough Clogs, Scum, Sludge AND Eliminates Odor...
Ease of use

9.1

5

9.1

Probiotic Enzyme Cleaner - Professional Strength Solution -One Gallon- Natural Bio-Enzymatic Stain & Odor Remover - No Rinse Fo...
Scent
Functionality
Cleaning power
Product quality

9.1

5
Probiotic Enzyme Cleaner - Professional Strength Solution -One Gallon- Natural Bio-Enzymatic Stain & Odor Remover - No Rinse Fo...
Scent
Functionality
Cleaning power
Product quality

9.0

6

9.0

Bio-Clean Drain Septic 2# Can Cleans Drains- Septic Tanks - Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! ...
Effectiveness
Drain cleaning
Drain flow
Ease of use
Safety

9.0

6
Bio-Clean Drain Septic 2# Can Cleans Drains- Septic Tanks - Grease Traps All Natural and 100% Guaranteed No Caustic Chemicals! ...
Effectiveness
Drain cleaning
Drain flow
Ease of use
Safety

8.9

7

8.9

Green Gobbler Drain Clog Remover | Toilet Clog Remover | Dissolve Hair & Organic Materials from Clogged Toilets, Sinks and Drai...
Functionality
Drain clarity
Ease of use
Smell
Water drainage

8.9

7
Green Gobbler Drain Clog Remover | Toilet Clog Remover | Dissolve Hair & Organic Materials from Clogged Toilets, Sinks and Drai...
Functionality
Drain clarity
Ease of use
Smell
Water drainage
Popular

8.7

8

8.7

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odor...
Smell
Functionality
Cleaning power
Value for money
Use
Ease of use
Popular

8.7

8
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odor...
Smell
Functionality
Cleaning power
Value for money
Use
Ease of use

8.6

9

8.6

Enzyme Drain Cleaner & Deodorizer for Sink Drain, Showers, Septic Systems, Bathroom & Kitchen - Smell Remover for Fruit Fly Gar...
Drain quality
Ease of use
Septic safety

8.6

9
Enzyme Drain Cleaner & Deodorizer for Sink Drain, Showers, Septic Systems, Bathroom & Kitchen - Smell Remover for Fruit Fly Gar...
Drain quality
Ease of use
Septic safety

8.5

10

8.5

Green Gobbler Fruit Fly Goodbye Gel Drain Treatment | Killer Flies & Eliminator (1 Gallon)
Functionality
Flies control
Ease of use
Smell
Gnat control
Drain cleaning
Save 13%
Save 13%

8.5

10
Green Gobbler Fruit Fly Goodbye Gel Drain Treatment | Killer Flies & Eliminator (1 Gallon)
Functionality
Flies control
Ease of use
Smell
Gnat control
Drain cleaning
Save 13%

Our Top Choice

Best Enzyme Drain Cleaner

10.0

1

10.0

Bioda Professional Strength Enzyme Drain Cleaner, Septic Safe Drain Odor Eliminator, Smell Eliminator
Functionality
Smell
Drain cleaning
Read Full Review
Picked by 354 people this week!
Picked by 354 people this week!
Picked by 354 people this week!
Best Enzyme Drain Cleaner

10.0

1
Bioda Professional Strength Enzyme Drain Cleaner, Septic Safe Drain Odor Eliminator, Smell Eliminator
Functionality
Smell
Drain cleaning
Picked by 354 people this week!
Read Full Review
Related Categories
Drain Cleaner for Drain FliesEnzyme CleanerDrain Fly KillerGarbage Disposal CleanerGrease Cleaner for PipesEnzyme Cleaner for Carpet
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Related Categories
Drain Cleaner for Drain FliesEnzyme CleanerDrain Fly KillerGarbage Disposal CleanerGrease Cleaner for PipesEnzyme Cleaner for Carpet
Related Categories
Drain Cleaner for Drain FliesEnzyme CleanerDrain Fly KillerGarbage Disposal CleanerGrease Cleaner for PipesEnzyme Cleaner for Carpet