Best Enzyme Cleaners for Cat Urine Updated March 2026
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Best Enzyme Cleaners for Cat Urine
2026 Buyer's GuideUpdated March 2026
Advertiser disclosure About our rankings
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Best Overall
1

10.0

Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Ha...
Effectiveness
Smell
Stain removal
Product quality
Spray effectiveness
Ease of application
Read Full Review
20% Coupon
7K+ bought in past month
Best Overall

10.0

1
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Ha...
Effectiveness
Smell
Stain removal
Product quality
Spray effectiveness
Ease of application
7K+ bought in past month
20% Coupon
Read Full Review
Best Overall

10.0

1
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Ha...
Read Full Review
Effectiveness
Smell
Stain removal
Product quality
Spray effectiveness
Ease of application
7K+ bought in past month
20% Coupon
2

9.9

Angry Orange Pet Odor Eliminator 8 oz. bottle- Industrial Strength Pet Odor Remover - Makes (4) 32oz. Bottles - 1 Gallon - Neut...
Smell
Effectiveness
Value for money
Odor elimination
Stain removal
Urine removal
Read Full Review
-11% + 20% Coupon

9.9

2
Angry Orange Pet Odor Eliminator 8 oz. bottle- Industrial Strength Pet Odor Remover - Makes (4) 32oz. Bottles - 1 Gallon - Neut...
Smell
Effectiveness
Value for money
Odor elimination
Stain removal
Urine removal
-11% + 20% Coupon
Read Full Review

9.9

2
Angry Orange Pet Odor Eliminator 8 oz. bottle- Industrial Strength Pet Odor Remover - Makes (4) 32oz. Bottles - 1 Gallon - Neut...
Available in:  2 scents
Read Full Review
Smell
Effectiveness
Value for money
Odor elimination
Stain removal
Urine removal
-11% + 20% Coupon
3

9.7

Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural En...
Smell
Works well
Detergent quality
Value for money
Washability
Urine removal
Read Full Review
-35% + $2 Coupon

9.7

3
Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural En...
Smell
Works well
Detergent quality
Value for money
Washability
Urine removal
-35% + $2 Coupon
Read Full Review

9.7

3
Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural En...
Read Full Review
Smell
Works well
Detergent quality
Value for money
Washability
Urine removal
-35% + $2 Coupon
4

9.6

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odor...
Smell
Effectiveness
Product quality
Stain removal
Value for money
Utility

9.6

4
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odor...
Smell
Effectiveness
Product quality
Stain removal
Value for money
Utility

9.6

4
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odor...
Available in:  2 sizes
Smell
Effectiveness
Product quality
Stain removal
Value for money
Utility
5

9.4

G's Cleaning Biodegradable Stain & Odor Remover Spray – 32 oz Pet Urine Enzyme Cleaner – Pet Odor Eliminator for Home – Cat & D...
Stain removal effectiveness
Product quality
Scent
5% Coupon

9.4

5
G's Cleaning Biodegradable Stain & Odor Remover Spray – 32 oz Pet Urine Enzyme Cleaner – Pet Odor Eliminator for Home – Cat & D...
Stain removal effectiveness
Product quality
Scent
5% Coupon

9.4

5
G's Cleaning Biodegradable Stain & Odor Remover Spray – 32 oz Pet Urine Enzyme Cleaner – Pet Odor Eliminator for Home – Cat & D...
Stain removal effectiveness
Product quality
Scent
5% Coupon
Premium Pick
Popular
6

9.2

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover fo...
Functionality
Odor elimination
Product quality
Stains removal
Cleaning ability
Read Full Review
Premium Pick
Popular

9.2

6
Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover fo...
Functionality
Odor elimination
Product quality
Stains removal
Cleaning ability
Read Full Review
Premium Pick
Popular

9.2

6
Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover fo...
Available in:  2 scents ,  2 sizes
Read Full Review
Functionality
Odor elimination
Product quality
Stains removal
Cleaning ability
7

9.1

Nature's Miracle Stain and Odor Remover Cat, Odor Control Formula, Pour
Effectiveness
Product quality
Stain removal
Value for money
Pet protection
Ease of use

9.1

7
Nature's Miracle Stain and Odor Remover Cat, Odor Control Formula, Pour
Effectiveness
Product quality
Stain removal
Value for money
Pet protection
Ease of use

9.1

7
Nature's Miracle Stain and Odor Remover Cat, Odor Control Formula, Pour
Available in:  2 sizes
Effectiveness
Product quality
Stain removal
Value for money
Pet protection
Ease of use
Best Value
8

8.9

Nature's Miracle Advanced Cat Stain and Odor Eliminator Spray, Severe Mess Enzymatic Formula, 32 fl oz
Works well
Product quality
Stain removal
Urine removal
Pet owners
-15%
Best Value

8.9

8
Nature's Miracle Advanced Cat Stain and Odor Eliminator Spray, Severe Mess Enzymatic Formula, 32 fl oz
Works well
Product quality
Stain removal
Urine removal
Pet owners
-15%
Best Value

8.9

8
Nature's Miracle Advanced Cat Stain and Odor Eliminator Spray, Severe Mess Enzymatic Formula, 32 fl oz
Available in:  2 scents ,  4 sizes
Works well
Product quality
Stain removal
Urine removal
Pet owners
-15%
9

8.8

KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Eff...
Effectiveness
Product quality
Urine removal
Ease of use
Washability

8.8

9
KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Eff...
Effectiveness
Product quality
Urine removal
Ease of use
Washability

8.8

9
KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Eff...
Available in:  3 scents ,  3 sizes
Effectiveness
Product quality
Urine removal
Ease of use
Washability
10

8.5

Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & C...
Smell
Works well
Stains removal
Quality
Value for money
Effectiveness
5% Coupon

8.5

10
Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & C...
Smell
Works well
Stains removal
Quality
Value for money
Effectiveness
5% Coupon

8.5

10
Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & C...
Available in:  2 scents ,  5 sizes
Smell
Works well
Stains removal
Quality
Value for money
Effectiveness
5% Coupon

Our Top Choice

Best Overall
1

10.0

Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Ha...
Effectiveness
Smell
Stain removal
Product quality
Spray effectiveness
Ease of application
Read Full Review
20% Coupon
7K+ bought in past month
Best Overall

10.0

1
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Ha...
Effectiveness
Smell
Stain removal
Product quality
Spray effectiveness
Ease of application
7K+ bought in past month
20% Coupon
Read Full Review
Best Overall

10.0

1
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Ha...
Read Full Review
Effectiveness
Smell
Stain removal
Product quality
Spray effectiveness
Ease of application
7K+ bought in past month
20% Coupon
Related Categories
Cat Urine DestroyerCarpet Urine RemoverCat Urine Remover for CarpetEnzymatic Pet CleanerEnzyme CleanerEnzyme Urine Remover
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