Best B12 Supplements Updated April 2026
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Best B12 Supplements
2026 Buyer's GuideUpdated April 2026
Advertiser disclosure About our rankings
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Best B12 Supplement
1

10.0

USDA Organic Vitamin B12 Sublingual Drops - 5000 mcg Liquid Vegan Methylcobalamin for Women & Men - Energy Boost, Focus & Mood,...
Taste
Quality
Energy
Effectiveness
Ease of use
Ingredients
-27%
6K+ bought in past month
Best B12 Supplement

10.0

1
USDA Organic Vitamin B12 Sublingual Drops - 5000 mcg Liquid Vegan Methylcobalamin for Women & Men - Energy Boost, Focus & Mood,...
Taste
Quality
Energy
Effectiveness
Ease of use
Ingredients
6K+ bought in past month
-27%
Best B12 Supplement

10.0

1
USDA Organic Vitamin B12 Sublingual Drops - 5000 mcg Liquid Vegan Methylcobalamin for Women & Men - Energy Boost, Focus & Mood,...
Available in:  3 styles
Taste
Quality
Energy
Effectiveness
Ease of use
Ingredients
6K+ bought in past month
-27%
Popular
2

9.8

L Methyl Folate 15mg Plus Methyl B12 Cofactor – High Potency, Active 5-MTHF Form - Supports Mood, Methylation, Cognition – Bioa...
Quality
Effectiveness
Energy
Value for money
Side effects
Ease of use
Popular

9.8

2
L Methyl Folate 15mg Plus Methyl B12 Cofactor – High Potency, Active 5-MTHF Form - Supports Mood, Methylation, Cognition – Bioa...
Quality
Effectiveness
Energy
Value for money
Side effects
Ease of use
Popular

9.8

2
L Methyl Folate 15mg Plus Methyl B12 Cofactor – High Potency, Active 5-MTHF Form - Supports Mood, Methylation, Cognition – Bioa...
Available in:  2 sizes ,  2 options
Quality
Effectiveness
Energy
Value for money
Side effects
Ease of use
3

9.6

USDA Organic Vitamin B-Complex B5 Pantothenic Acid | B12 Methylcobalamin | B1 Thiamine | B6 Pyridoxine | B7 Biotin | B9 Folic |...
Quality
Energy
Effectiveness
Ease of use
Mood
B complex
-27%

9.6

3
USDA Organic Vitamin B-Complex B5 Pantothenic Acid | B12 Methylcobalamin | B1 Thiamine | B6 Pyridoxine | B7 Biotin | B9 Folic |...
Quality
Energy
Effectiveness
Ease of use
Mood
B complex
-27%

9.6

3
USDA Organic Vitamin B-Complex B5 Pantothenic Acid | B12 Methylcobalamin | B1 Thiamine | B6 Pyridoxine | B7 Biotin | B9 Folic |...
Available in:  3 styles
Quality
Energy
Effectiveness
Ease of use
Mood
B complex
-27%
Premium Pick
4

9.5

(2 Pack) Vitamin B12 and B6 Liquid Drops, B12 Sublingual Vitamin B Complex - B 12 Vitamin 5000mcg - B12 Methylcobalamin for Ene...
Quality
Energy
Effectiveness
Ease of use
Value for money
Mood
20% Coupon
Premium Pick

9.5

4
(2 Pack) Vitamin B12 and B6 Liquid Drops, B12 Sublingual Vitamin B Complex - B 12 Vitamin 5000mcg - B12 Methylcobalamin for Ene...
Quality
Energy
Effectiveness
Ease of use
Value for money
Mood
20% Coupon
Premium Pick

9.5

4
(2 Pack) Vitamin B12 and B6 Liquid Drops, B12 Sublingual Vitamin B Complex - B 12 Vitamin 5000mcg - B12 Methylcobalamin for Ene...
Available in:  2 sizes ,  7 options
Quality
Energy
Effectiveness
Ease of use
Value for money
Mood
20% Coupon
5

9.4

EZ Melts Dissolvable B12 2,500 mcg - Vitamin B12 for Energy & Immune Support - Non-GMO, Vegan & Gluten-Free - Red Cherry - 90 S...
Taste
Solubility
Quality
Ease of use
Effectiveness
Energy
10% Coupon

9.4

5
EZ Melts Dissolvable B12 2,500 mcg - Vitamin B12 for Energy & Immune Support - Non-GMO, Vegan & Gluten-Free - Red Cherry - 90 S...
Taste
Solubility
Quality
Ease of use
Effectiveness
Energy
10% Coupon

9.4

5
EZ Melts Dissolvable B12 2,500 mcg - Vitamin B12 for Energy & Immune Support - Non-GMO, Vegan & Gluten-Free - Red Cherry - 90 S...
Available in:  2 sizes
Taste
Solubility
Quality
Ease of use
Effectiveness
Energy
10% Coupon
6

9.1

Nature Made Vitamin B12 1000 mcg, B12 Vitamins, Dietary Supplement for Energy Metabolism Support, 160 Time Release Tablets, 160...
Quality
Value for money
Ease of swallowing
Effectiveness
Energy boost
Health benefits
-10%

9.1

6
Nature Made Vitamin B12 1000 mcg, B12 Vitamins, Dietary Supplement for Energy Metabolism Support, 160 Time Release Tablets, 160...
Quality
Value for money
Ease of swallowing
Effectiveness
Energy boost
Health benefits
-10%

9.1

6
Nature Made Vitamin B12 1000 mcg, B12 Vitamins, Dietary Supplement for Energy Metabolism Support, 160 Time Release Tablets, 160...
Available in:  2 sizes
Quality
Value for money
Ease of swallowing
Effectiveness
Energy boost
Health benefits
-10%
Best Value
7

8.9

Vitamatic Vitamin B12 1000 mcg Fast Dissolve – 365 Tablets – Natural Berry Flavor – Supports Energy Metabolism & Nervous System...
Value for money
Taste
Quality
Dissolvability
Ease of use
Effectiveness
10% Coupon
Best Value

8.9

7
Vitamatic Vitamin B12 1000 mcg Fast Dissolve – 365 Tablets – Natural Berry Flavor – Supports Energy Metabolism & Nervous System...
Value for money
Taste
Quality
Dissolvability
Ease of use
Effectiveness
10% Coupon
Best Value

8.9

7
Vitamatic Vitamin B12 1000 mcg Fast Dissolve – 365 Tablets – Natural Berry Flavor – Supports Energy Metabolism & Nervous System...
Available in:  3 styles
Value for money
Taste
Quality
Dissolvability
Ease of use
Effectiveness
10% Coupon
8

8.8

BioActive Vitamin B12 - 5000 mcg, Contains 3 BioActive Forms B12 Plus Methylfolate Cofactor - Methyl B12, Adenosyl B12 & Hydrox...
Quality
Energy
Effectiveness
Digestibility
B12 content
Ease of use

8.8

8
BioActive Vitamin B12 - 5000 mcg, Contains 3 BioActive Forms B12 Plus Methylfolate Cofactor - Methyl B12, Adenosyl B12 & Hydrox...
Quality
Energy
Effectiveness
Digestibility
B12 content
Ease of use

8.8

8
BioActive Vitamin B12 - 5000 mcg, Contains 3 BioActive Forms B12 Plus Methylfolate Cofactor - Methyl B12, Adenosyl B12 & Hydrox...
Quality
Energy
Effectiveness
Digestibility
B12 content
Ease of use
9

8.7

Sports Research® Vitamin B-Complex - Full Spectrum of B Vitamins with Methylated B12 & Folate - Gluten Free · Plant-Based · Non...
Quality
Energy
Ingredients
Effectiveness
Ease of use
-20%

8.7

9
Sports Research® Vitamin B-Complex - Full Spectrum of B Vitamins with Methylated B12 & Folate - Gluten Free · Plant-Based · Non...
Quality
Energy
Ingredients
Effectiveness
Ease of use
-20%

8.7

9
Sports Research® Vitamin B-Complex - Full Spectrum of B Vitamins with Methylated B12 & Folate - Gluten Free · Plant-Based · Non...
Available in:  2 sizes
Quality
Energy
Ingredients
Effectiveness
Ease of use
-20%
10

8.4

THORNE - Vitamin B12 - as Methylcobalamin - Supports Heart & Nerve Health, Blood Cell Function, Restful Sleep & Methylation* - ...
Quality
Effectiveness
Stomach sensitivity
Energy level
Value for money
Ease of swallow

8.4

10
THORNE - Vitamin B12 - as Methylcobalamin - Supports Heart & Nerve Health, Blood Cell Function, Restful Sleep & Methylation* - ...
Quality
Effectiveness
Stomach sensitivity
Energy level
Value for money
Ease of swallow

8.4

10
THORNE - Vitamin B12 - as Methylcobalamin - Supports Heart & Nerve Health, Blood Cell Function, Restful Sleep & Methylation* - ...
Quality
Effectiveness
Stomach sensitivity
Energy level
Value for money
Ease of swallow

Our Top Choice

Best B12 Supplement
1

10.0

USDA Organic Vitamin B12 Sublingual Drops - 5000 mcg Liquid Vegan Methylcobalamin for Women & Men - Energy Boost, Focus & Mood,...
Taste
Quality
Energy
Effectiveness
Ease of use
Ingredients
-27%
6K+ bought in past month
Best B12 Supplement

10.0

1
USDA Organic Vitamin B12 Sublingual Drops - 5000 mcg Liquid Vegan Methylcobalamin for Women & Men - Energy Boost, Focus & Mood,...
Taste
Quality
Energy
Effectiveness
Ease of use
Ingredients
6K+ bought in past month
-27%
Best B12 Supplement

10.0

1
USDA Organic Vitamin B12 Sublingual Drops - 5000 mcg Liquid Vegan Methylcobalamin for Women & Men - Energy Boost, Focus & Mood,...
Available in:  3 styles
Taste
Quality
Energy
Effectiveness
Ease of use
Ingredients
6K+ bought in past month
-27%
Related Categories
B12 Supplement for WomenVitamin B12 SupplementSublingual B12 SupplementMethylcobalamin B12 SupplementB12 DropsB12 Liquid Drops
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Related Categories
B12 Supplement for WomenVitamin B12 SupplementSublingual B12 SupplementMethylcobalamin B12 SupplementB12 DropsB12 Liquid Drops
Related Categories
B12 Supplement for WomenVitamin B12 SupplementSublingual B12 SupplementMethylcobalamin B12 SupplementB12 DropsB12 Liquid Drops