Best Enzyme Cleaners Updated February 2026
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Best Enzyme Cleaners
2026 Buyer's GuideUpdated February 2026
Advertiser disclosure About our rankings
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Best Enzyme Cleaner
1

10.0

Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Ha...
Eliminates: Odors, stains, & residue
Scent: Citrus
Application: Spray
For Use On: Carpet, wood floors, upholstery, mattress, dog bed, and more
Read Full Review
20% Coupon
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5K+ bought in past month
Best Enzyme Cleaner

10.0

1
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Ha...
Eliminates: Odors, stains, & residue
Scent: Citrus
Application: Spray
For Use On: Carpet, wood floors, upholstery, mattress, dog bed, and more
5K+ bought in past month
20% Coupon
Compare
Read Full Review
Popular
2

9.8

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover fo...
Eliminates: Odors, stains, & residue
Scent: Fresh
Application: Spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more
Read Full Review
$2 Coupon
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Popular

9.8

2
Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover fo...
Eliminates: Odors, stains, & residue
Scent: Fresh
Application: Spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more
$2 Coupon
Compare
Read Full Review
3

9.5

Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural En...
Eliminates: Odors
Scent: Unscented
Application: Laundry detergent
For Use On: Pet beds, blankets, rugs, upholstery, furniture covers
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Save 14% + $2 Coupon
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9.5

3
Pet Laundry Detergent Odor Remover - ACTIVE Enzyme Based Powder Detergent for Dogs Beds, Cat Pee, HE Washer Friendly Natural En...
Eliminates: Odors
Scent: Unscented
Application: Laundry detergent
For Use On: Pet beds, blankets, rugs, upholstery, furniture covers
Save 14% + $2 Coupon
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Read Full Review
4

9.3

Nature's Miracle Stain and Odor Remover for Dogs, Odor Control Formula, Refill, 1.33 Gal
Eliminates: Odors, stains, & residue
Scent: Citrus
Application: Spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more
Save 16%
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9.3

4
Nature's Miracle Stain and Odor Remover for Dogs, Odor Control Formula, Refill, 1.33 Gal
Eliminates: Odors, stains, & residue
Scent: Citrus
Application: Spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more
Save 16%
Compare
5

9.2

AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
Eliminates: Odors, stains, & residue
Scent: Mint
Application: Spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more
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9.2

5
AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
Eliminates: Odors, stains, & residue
Scent: Mint
Application: Spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more
Compare
Premium Pick
6

9.0

KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Eff...
Eliminates: Odors, stains, & residue
Scent: Citrus, lavender, or original
Application: Spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more
10% Coupon
Compare
Premium Pick

9.0

6
KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Eff...
Eliminates: Odors, stains, & residue
Scent: Citrus, lavender, or original
Application: Spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more
10% Coupon
Compare
Best Value
7

8.9

Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Activ...
Eliminates: Odors, stains, & residue
Scent: Unscented
Application: Add to laundry
For Use On: Clothing, pet beds, blankets, upholstery & furniture covers
Save 15% + 15% Coupon
Compare
Best Value

8.9

7
Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Activ...
Eliminates: Odors, stains, & residue
Scent: Unscented
Application: Add to laundry
For Use On: Clothing, pet beds, blankets, upholstery & furniture covers
Save 15% + 15% Coupon
Compare
8

8.7

BugMD Enzyme Cleaner for Dog & Cat Urine | Pet Stain and Odor Remover for Carpet & Home | Unscented Urine Destroyer & Deodorize...
Eliminates: Odors, stains, & residue
Scent: Unscented
Application: Spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more
15% Coupon
Compare

8.7

8
BugMD Enzyme Cleaner for Dog & Cat Urine | Pet Stain and Odor Remover for Carpet & Home | Unscented Urine Destroyer & Deodorize...
Eliminates: Odors, stains, & residue
Scent: Unscented
Application: Spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more
15% Coupon
Compare
9

8.5

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odor...
Eliminates: Odors, stains, & residue
Scent: Lemon
Application: Mix with water & spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, and more
Compare

8.5

9
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odor...
Eliminates: Odors, stains, & residue
Scent: Lemon
Application: Mix with water & spray
For Use On: Carpet, wood floor, upholstery, mattress, dog bed, and more
Compare
10

8.4

Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & C...
Eliminates: Odors, stains, & residue
Scent: Unscented
Application: Spray
For Use On: Carpet, wood floors, upholstery, dog bed, and more
5% Coupon
Compare

8.4

10
Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & C...
Eliminates: Odors, stains, & residue
Scent: Unscented
Application: Spray
For Use On: Carpet, wood floors, upholstery, dog bed, and more
5% Coupon
Compare
We also considered 6 others:

Our Top Choice

Best Enzyme Cleaner
1

10.0

Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Ha...
Eliminates: Odors, stains, & residue
Scent: Citrus
Application: Spray
For Use On: Carpet, wood floors, upholstery, mattress, dog bed, and more
Read Full Review
20% Coupon
Compare
5K+ bought in past month
Best Enzyme Cleaner

10.0

1
Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Ha...
Eliminates: Odors, stains, & residue
Scent: Citrus
Application: Spray
For Use On: Carpet, wood floors, upholstery, mattress, dog bed, and more
5K+ bought in past month
20% Coupon
Compare
Read Full Review

Compare Features

Application
Best Enzyme Cleaner
1. ACTIVE Pet Odor and Stain Eliminator
ACTIVE Preview ACTIVE Preview
ACTIVE
at Amazon
Popular
2. Rocco & Roxie Supply Co. Stain & Odor Eliminator
ROCCO & ROXIE Preview ROCCO & ROXIE Preview
ROCCO & ROXIE
at Amazon
3. ACTIVE Pet Laundry Detergent Odor Remover
ACTIVE Preview ACTIVE Preview
ACTIVE
at Amazon
4. Nature's Miracle Stain and Odor Remover Refill
NATURE'S MIRACLE Preview NATURE'S MIRACLE Preview
NATURE'S MIRACLE
at Amazon
5. AmazonCommercial Multi-Purpose Enzyme Cleaner
AMAZONCOMMERCIAL Preview AMAZONCOMMERCIAL Preview
AMAZONCOMMERCIAL
at Amazon
Premium Pick
6. KINZUA ENVIRONMENTAL Urine B-Gone Cleaner
URINE-B-GONE Preview URINE-B-GONE Preview
URINE-B-GONE
at Amazon
Best Value
7. ACTIVE Enzyme Laundry Booster
ACTIVE Preview ACTIVE Preview
ACTIVE
at Amazon
8. BugMD Enzyme Stain & Odor Eliminator
BUGMD Preview BUGMD Preview
BUGMD
at Amazon
9. Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer
BIODA Preview BIODA Preview
BIODA
at Amazon
10. Simple Solution Extreme Pet Stain and Odor Eliminator Spray
SIMPLE SOLUTION Preview SIMPLE SOLUTION Preview
SIMPLE SOLUTION
at Amazon
Deal
20% Coupon $2 Coupon Save 14% + $2 Coupon Save 16% — 10% Coupon Save 15% + 15% Coupon 15% Coupon — 5% Coupon
Deal 20% Coupon $2 Coupon Save 14% + $2 Coupon Save 16% — 10% Coupon Save 15% + 15% Coupon 15% Coupon — 5% Coupon
Eliminates
Odors, stains, & residue Odors, stains, & residue Odors Odors, stains, & residue Odors, stains, & residue Odors, stains, & residue Odors, stains, & residue Odors, stains, & residue Odors, stains, & residue Odors, stains, & residue
Eliminates 		Odors, stains, & residue Odors, stains, & residue Odors Odors, stains, & residue Odors, stains, & residue Odors, stains, & residue Odors, stains, & residue Odors, stains, & residue Odors, stains, & residue Odors, stains, & residue
Scent
Citrus Fresh Unscented Citrus Mint Citrus, lavender, or original Unscented Unscented Lemon Unscented
Scent 		Citrus Fresh Unscented Citrus Mint Citrus, lavender, or original Unscented Unscented Lemon Unscented
Application
Spray Spray Laundry detergent Spray Spray Spray Add to laundry Spray Mix with water & spray Spray
Application 		Spray Spray Laundry detergent Spray Spray Spray Add to laundry Spray Mix with water & spray Spray
For Use On
Carpet, wood floors, upholstery, mattress, dog bed, and more Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more Pet beds, blankets, rugs, upholstery, furniture covers Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more Clothing, pet beds, blankets, upholstery & furniture covers Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more Carpet, wood floor, upholstery, mattress, dog bed, and more Carpet, wood floors, upholstery, dog bed, and more
For Use On 		Carpet, wood floors, upholstery, mattress, dog bed, and more Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more Pet beds, blankets, rugs, upholstery, furniture covers Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more Clothing, pet beds, blankets, upholstery & furniture covers Carpet, wood floor, upholstery, mattress, dog bed, clothing, and more Carpet, wood floor, upholstery, mattress, dog bed, and more Carpet, wood floors, upholstery, dog bed, and more

Related Categories
Enzyme Cleaner for CarpetCat Urine Enzymatic CleanerEnzyme Urine RemoverEnzymatic Pet CleanerEnzyme Cleaner for Cat UrineCat Urine Odor Eliminator
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Related Categories
Enzyme Cleaner for CarpetCat Urine Enzymatic CleanerEnzyme Urine RemoverEnzymatic Pet CleanerEnzyme Cleaner for Cat UrineCat Urine Odor Eliminator
Related Categories
Enzyme Cleaner for CarpetCat Urine Enzymatic CleanerEnzyme Urine RemoverEnzymatic Pet CleanerEnzyme Cleaner for Cat UrineCat Urine Odor Eliminator